Adme And Translational Pharmacokinetics / Pharmacodynamics Of Therapeutic Proteins: Applications In Drug Discovery And Development

"This book focuses on the fundamental and practical aspects of ADME and translational PK/PD for therapeutic proteins -- cutting-edge research, lessons learned from small molecules, the utility of ADME and translational PK/PD to guide lead optimization, first-in-human study dose projection and design, and clinical development and registration"--Provided by publisher.

Honghui Zhou is a Senior Director and Janssen Fellow, at Janssen Research & Development, LLC and head of the Pharmacological and Translational Modeling Department. Board-certified by the American Board of Clinical Pharmacology and a Fellow of American Association of Pharmaceutical Scientists (AAPS) and American College of Clinical Pharmacology (ACCP), Dr. Zhou has authored more than 180 peer-reviewed scientific papers, book chapters, and conference abstracts and co-edited the bookDrug-Drug Interactions for Therapeutic Biologics (Wiley, 2013).

Frank-Peter Theil heads nonclinical development at UCB Pharma. Dr. Theil has authored and co-authored 40 research publications, three book chapters and he has given numerous invited presentations at national and international scientific meetings. He is a member of the American Association of Pharmaceutical Scientists (AAPS) and American Society of Clinical Pharmacology and Therapeutics (ASCPT).