定 價：NT$ 1105 元
優惠價：90 折 995 元
領券後再享88折
領
團購優惠券A
8本以上且滿1500元
再享89折，單本省下109元
再享89折，單本省下109元
領
無庫存，下單後進貨(採購期約45個工作天)
可得紅利積點：29 點
相關商品
商品簡介
商品簡介
The metabolic activation of many drugs and xenobiotics in vivo is effected through the large family of cytochrome P450s enzymes that catalyse a diverse spectrum of reactions including the metabolism of both endogenous and exogenous compounds. There is considerable evidence suggesting that changes in P450 activities can affect the in vivo toxicity of drugs in both animals and humans. Oxidative metabolism by cytochrome P450 enzymes has been implicated in the pathogenesis of cancer, through the formation of toxic intermediates and carcinogenic metabolites are formed from drugs and xenobiotics. A marked overall increase in the metabolic activation of the commonly used analgesic agent, paracetamol, was found in patients with hepatocellular carcinoma, as indicated by a much higher percentage recovery of the oxidative metabolites cysteine and mercapturate conjugates, compared to healthy controls and patients with chronic hepatitis B infection. It was through that metabolic activation of some drugs and xenobiotics through the actions of specific cytochrome P450s may be enhanced in patients with hepatocellular carcinoma.
您曾經瀏覽過的商品
購物須知
無庫存之港版書籍，將需向海外調貨，平均作業時間約30個工作天，然不保證確定可調到貨，尚請見諒。
為了縮短等待時間，建議您將港書與一般繁體書籍分開下單，以獲得最快的取貨速度。
為了保護您的權益，「三民網路書店」提供會員七日商品鑑賞期(收到商品為起始日)。
若要辦理退貨，請在商品鑑賞期內寄回，且商品必須是全新狀態與完整包裝(商品、附件、發票、隨貨贈品等)否則恕不接受退貨。