While a full time law professor, DuBoff was also Of Counsel to law firms and maintained that relationship until 1994 when he left full-time teaching to found his own law firm that specializes in business and intellectual property law. DuBoff has received academic awards from President Lyndon Johnson, New York Governor Nelson Rockefeller, and in 1990, he received the Governor's Arts Award from Oregon Governor Neil Goldschmidt.
In addition to practicing law, DuBoff has also been involved in its creation. In the late 1980s, he testified in support of the Visual Artist's Rights Act of 1990, at the request of Senator Edward Kennedy of Massachusetts. He has also provided Conress with testimony related to several cultural and intellectual property treaties and he has worked with state legislatures on their legislation as well.
A prolific author, DuBoff has written numerous articles for scholarly journals, practical articles for lawyers bar publications and articles for nonlawyers as well. He has regular columns in several publications. He is coauthor of the law school text-Cases and Materials on Art Law.