Handbook of Nanophysics: Nanomedicine and Nanorobotics

The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nanotechnology to molecular and biological processes, medical imaging, targeted drug delivery, and cancer treatment. Each peer-reviewed chapter contains a broad-based introduction and enhances understanding of the state-of-the-art scientific content through fundamental equations and illustrations, some in color.

This volume shows how the materials, tools, and techniques of nanotechnology, such as enzymatic nanolithography, biomimetic approaches, and force spectroscopy, are currently used in biological applications, including living cell biochips, biosensors, protein recognition, and the analysis of biomolecules. Drawing on emerging toxicology research, it examines the impact and risks of nanomaterials on human health and the environment. Researchers at the forefront of the field cover tissue engineering, diagnostic, drug delivery, and therapeutic applications, including organs derived from nanomaterials, quantum dots and magnetic nanoparticles for imaging, pharmaceutical nanocarriers, targeted magnetic particles and biodegradable nanoparticles for drug delivery, and cancer treatment using gold nanoparticles. They also explain how cells and skin respond to these nanomaterials.

In addition, the book investigates the next generation of nanotechnology research that is focused on nanorobotics and its potential in detecting and destroying cancer cells and detecting and measuring toxic chemicals. It considers the roles nanoheaters, nanomotors, and nanobatteries can play in this new technology.
Nanophysics brings together multiple disciplines to determine the structural, electronic, optical, and thermal behavior of nanomaterials; electrical and thermal conductivity; the forces between nanoscale objects; and the transition between classical and quantum behavior. Facilitating communication across many disciplines, this landmark publication encourages scientists with disparate interests to collaborate on interdisciplinary projects and incorporate the theory and methodology of other areas into their work.

Klaus D. Sattler is a professor of physics at the University of Hawaii-Manoa in Honolulu. A pioneer in nanophysics, Dr. Sattler built the first atomic cluster source in 1980, which became a cornerstone for nanoscience and nanotechnology. In 1994, his research group at the University of Hawaii produced the first carbon nanocones. His current research focuses on novel nanomaterials, tunneling spectroscopy of quantum dots, and solar photocatalysis with nanoparticles for the purification of water. Dr. Sattler has been a recipient of the Walter Schottky Prize from the German Physical Society

Nano-Bio InterfacingQuantum Dots: Basics to Biological Applications, Sarwat B. Rizvi, Mo Keshtgar, and Alexander Marcus SeifalianViral Biology and Nanotechnology, Vaibhav Saini and Maaike EvertsNano-Bio Interfacing with Living Cell Biochips, Yosi Shacham-Diamand, Ronen Almog, Ramiz Daniel, Arthur Rabner, and Rachela PopovtzerMicro- and Nanomechanical Biosensors, Maria Arroyo-Hernandez, Priscila M. Kosaka, Johann Mertens, Montserrat Calleja, and Javier TamayoEnzymatic Nanolithography, Manfred RadmacherBiomimetic Synthesis of Nanostructures Inspired by Biomineralization, Eike Brunner, Hermann Ehrlich, and Martin KammerNanotubes for Biotechnology, Jonathan C.G. Jeynes, Vanesa Sanz-Beltran, Johnjoe McFadden, and S.R.P. SilvaNanoscale Forces in Protein Recognition and Adhesion, Deborah LeckbandForce Spectroscopy on Cells, Martin BenoitNanoscale Magnetic Biotransport, Edward P. FurlaniNanomechanical Sensors for Biochemistry and Medicine, Hans Peter Lang and Christoph GerberAnalyzing Individual Biomolecules Using Nanopores, Meni Wanunu, Gautam V. Soni, and Amit Meller
NanotoxicologyChances and Risks of Nanotechnology, Armin GrunwaldHuman and Natural Environment Effects of Nanomaterials, Birgit Gaiser, Martin J.D. Clift , Helinor J. Johnston, Matthew S.P. Boyles, and Teresa F. FernandesToxicology, Diagnostics, and Therapy Functions of Nanomaterials, Stefano BellucciCell Oxidative Stress: Risk of Metal Nanoparticles, Marija Poljak-Blazi, Morana Jaganjac, and Neven ZarkovicFullerene C60 Toxicology, Crystal Y. Usenko, Stacey L. Harper, Michael T. Simonich, and Robert L. Tanguay
Clinical Significance of NanosystemsPharmacological Significance of Nanoparticles, Carlos Medina and Marek W. RadomskiOrgans from Nanomaterials, Maqsood Ahmed and Alexander Marcus SeifalianNanotechnology for Implants, Lijie Zhang and Thomas J. WebsterNanotechnology for the Urologist, Hashim Uddin Ahmed, Lyndon Gommersall, Iqbal S. Shergill, Manit Arya, and Mark Emberton
Medical ImagingQuantum Dots for Nanomedicine. Sarah H. Radwan and Hassan M.E. AzzazyRelaxivity of Nanoparticles for Magnetic Resonance Imaging, Gustav J. Strijkers and Klaas NicolayNanoparticle Contrast Agents for Medical Imaging, David P. Cormode, Willem J.M. Mulder, and Zahi A. FayadOptical Nanosensors for Medicine and Health Effect Studies, Tuan Vo-Dinh and Yan Zhang
Drug DeliveryMultifunctional Pharmaceutical Nanocarriers, Vladimir P. TorchilinNanotechnology and Drug Delivery, Fahima Dilnawaz, Sarbari Acharya, Ranjita Misra, Abhalaxmi Singh, and Sanjeeb Kumar SahooTargeting Magnetic Particles for Drug Delivery, Javed Ally and Alidad AmirfazliBiodegradable Nanoparticles for Drug Delivery, Jason Park and Tarek M. Fahmy
Response to NanomaterialsUptake of Carbon-Based Nanoparticles by Mammalian Cells and Plants, Pu-Chun Ke, Sijie Lin, Jason Reppert, Apparao M. Rao, and Hong LuoPenetration of Metallic Nanomaterials in Skin, Biancamaria BaroliNanoparticulate Systems and the Dermal Barrier, Frank Stracke and Marc SchneiderCellular Response to Continuous Nanostructures, Kevin J. Chalut, Karina Kulangara, and Kam W. Leong
Cancer TherapyNanotechnology for Targeting Cancer, Venkataramanan Soundararajan and Ram SasisekharanCancer Nanotechnology: Targeting Tumors with Nanoparticles, Erem BilensoyGold Nanoparticles for Plasmonic Photothermal Cancer Therapy, Xiaohua Huang, Ivan H. El-Sayed, and Mostafa A. El-SayedFullerenes in Photodynamic Therapy of Cancer, Pawel Mroz, Ying-Ying Huang, Tim Wharton, and Michael R. Hamblin
Quantum Engines and NanomotorsEnergy Transport and Heat Production in Quantum Engines, Liliana Arrachea and Michael MoskaletsArtificial Chemically Powered Nanomotors, Yu-Guo Tao and Raymond KapralNanobatteries, Dale Teeters and Paige L. JohnsonNanoheaters, Christian Falconi
NanoroboticsAtomic-Force-Microscopy-Based Nanomanipulation Systems, Cagdas D. Onal, Onur Ozcan, and Metin SittiNanomanipulation and Nanorobotics with the Atomic Force Microscope, Robert W. StarkNanorobotic Manipulation, Lixin Dong and Bradley J. NelsonMRI-Guided Nanorobotic Systems for Drug Delivery, Panagiotis Vartholomeos, Matthieu Fruchard, Antoine Ferreira, and Constantinos MavroidisMedical Micro- and Nanorobots, Sylvain MartelNanohandling Robot Cells, Sergej Fatikow, Thomas Wich, Christian Dahmen, Daniel Jasper, Christian Stolle, Volkmar Eichhorn, Saskia Hagemann, and Michael Weigel-Jech
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