Organic Synthesis With Carbohydrates

In a subject dominated by volumes at research and professional level, this book provides a broad understanding of the use of carbohydrates in organic synthesis, at postgraduate student level. Emphasis is placed on retrosynthetic analysis, with discussion of why a particular synthetic route has been chosen, and mechanistic explanations are provided for key and novel reactions. Wherever possible, the authors highlight points of general significance to organic synthesis. Selected experimental conditions and reaction details are incorporated to ensure that information can be utilised in research.

The book is extensively referenced and so provides a convenient point of entry to the primary literature.

1 Mono- and oligosaccharides: structure, configuration and conformation.

2 Protecting groups.

3 Functionalised saccharides.

4 Oligosaccharide synthesis.

5 The chemistry of O- and N-linked glycopeptides.

Part B: Natural Product Synthesis from Monosaccharides.

6 (-)-Echinosporin.

7 (+)Zaragozic acid C.

8 (+)-Neocarzinostatin.

9 (+)-Castanospermine.

10 (-)-Silphiperfolene.

11 (-)-Allosamizoline.

12 (-)-Reiswigin A.

13 (-)-Octalactin A.

14 (-)-ACRL toxin I.

15 (+)-Gasbosine E.

16 (-)-Augustamine and (-)-amabiline.

17 (-)-FK506.

18 (3S, 5S)-5-Hydroxypiperazic acid.

References.

Index.