Indocyanine Green Injection (ICG). Tumor Detection Potential of ICG-navigated Imaging in Liver Surgery for Metastatic Lesions

Master's Thesis from the year 2022 in the subject Medicine - Other, grade: Master, University of Ghent, language: English, abstract: This review aims to evaluate the tumor detection potential of ICG-navigated imaging in liver surgery for metastatic lesions. Fluorescence imaging is an intraoperative guidance method used for malignancy detection with increasing potential. Indocyanine-green (ICG) is a fluorescent dye with FDA approval and is commonly used in various medical procedures, including segmental hepatectomy and liver metastasectomies. Medical databases, including PubMed, Embase, Web of Science, and Cochrane Library, were searched in July 2022. Articles analyzing the performance of ICG-guided surgeries in patients with liver metastases were eligible for inclusion. Tumor detection, diagnostic improvement, and margin-free tumor resection rates of ICG-guided imaging were evaluated and compared with preoperative and other intraoperative diagnostic methods.