Handbook of Enhanced Spectroscopy

Techniques such as Raman, infrared, fluorescence, and even nonlinear spectroscopies have recently grown in resolution and possibilities thanks to the use of nanostructured surfaces. The excitation of localized surface plasmon and the use of specific shapes of nanostructures have made it possible to gain an incredible sensitivity in these spectroscopic techniques. This book provides the reader with an overview of enhanced spectroscopies. Following an introduction to plasmon and electromagnetic effects arising in metallic nanostructures, it reviews the spectroscopic techniques enhanced by the presence of either a nanostructure or a tip.

Marc Lamy de la Chapelle is professor at Universite Paris 13, France, in the Laboratory of Chemistry, Properties and Structure of Biomaterials and Therapeutics Agents (UMR 7244). He received his PhD in science physics in 1998 from the University of Nantes, France, on the study of carbon nanotubes by Raman spectroscopy. His research activities are focused on nanooptics and Raman spectroscopy. His research subject is the application of surface-enhanced Raman spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS) to biological issues, especially to disease diagnosis. He is head of the Spectroscopies of Biomolecules and Biological Media research team and director of the CNRS national research network on Molecular Plasmonics and Enhanced Spectroscopies.

Nathalie Lidgi-Guigui is associate professor at Universite Paris 13 in the Laboratory of Chemistry, Properties and Structure of Biomaterials and Therapeutics Agents (UMR 7244). She received her PhD in material sciences in 2005 from the Unite Mixte de Physique CNRS-Thales, France, on the study of the electronic transport through an assembly of nanoparticles embedded in a tunnel barrier. During her postdoc at the University of Birmingham, UK, and the University of Evry, France, she used atomic force microscopy to study the coupling between biomolecular assemblies and nanoparticles. She joined Prof. Lamy de la Chapelle’s group in 2011. Her main research topics are dealing with surface structuration using innovative lithography techniques, molecular plasmonics, and the application of SERS to biosensing.

Pietro G. Gucciardi is senior researcher and coordinator of the Spectroscopy, Imaging and Trapping group at the Istituto per i Processi Chimico Fisici, Italy. He has extensive experience in near-field optical microscopy and plasmon-enhanced spectroscopies. He has employed polarization-sensitive techniques to understand the re-radiation enhancement in SERS and depolarization phenomena in TERS. His research includes the combination of optical tweezers with Raman/SERS spectroscopy for the analysis of individual nanostructures and the development of advanced nanobiosensors.