Applying Pharmacogenomics in Therapeutics

The implementation of pharmacogenomics in therapeutics offers the potential for clinicians and researchers to better predict the differences in drug response, resistance, efficacy, and toxicity and to optimize the treatment regimens based on these differences. With a focus on therapeutics based on the latest clinical evidence and guidelines, this book demonstrates how to apply the principles of pharmacogenomics in patient care. Patient case profiles elucidate the principles of pharmacogenomic biotechnology and testing and explain the concept of personal pharmacology. The book includes study questions and a summary of key points for each chapter.

Xiaodong Feng, PhD, PharmD, began his biomedical research career 19 years ago in the Wound Healing Center, Stony Brook School of Medicine, Stony Brook, New York, USA. He then served for four years as assistant professor in the Department of Dermatology at the State University of New York at Stony Brook, USA. Currently, Dr. Feng is professor of Pharmacology and Oncology, and Associate Dean at California Northstate University College of Medicine, Elk Grove, USA; clinical pharmacist at Sutter Davis Hospital, California, USA; and oncology pharmacy specialist at Dignity Health Medical Foundation, Rancho Cordova, California, USA.

Hong-Guang Xie, MD, PhD, earned his degrees from Central South University Xiangya School of Medicine, Changsha, China, was promoted to lecturer, and then to associate professor of pharmacology. Subsequently, he served as co-founder and associate director of the Pharmacogenetics Research Institute, Changsha, China; postdoctoral research fellow and faculty research instructor at Vanderbilt University, Nashville, Tennessee, USA; staff research fellow at the University of California Washington Center, DC, USA; and Oak Ridge Institute for Science and Education (ORISE) fellow for the United States Food and Drug Administration (US FDA). Dr. Xie is currently full professor of pharmacology and chief of the General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, China.