Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to chal
William Osler, who was a brilliant, innovative teacher and a scholar of the natural history of disease, revolutionized the art of practicing medicine at the bedside of his patients. He was idolized b
Get a quick, expert overview of risk management in transfusion medicine from Dr. James Mills Barbeau. This practical resource presents a summary of today's state-of-the-art techniques for reducing har
In this pithy abecedarium, doctor and poet Iain Bamforth takes a close look at the conflict of values embodied in what we call medicine—never entirely a science and no longer quite the art it used to
Genes and Common Diseases presents an up-to-date view of the role of genetics in modern medicine, reflecting the strengths and limitations of a genetic perspective. The current shift in emphasis from the study of rare single gene disorders to common diseases brings genetics into every aspect of modern medicine, from infectious diseases to therapeutics. However, it is unclear whether this increasingly genetic focus will prove useful in the face of major environmental influences in many common diseases. The book takes a hard and self-critical look at what can and cannot be achieved using a genetic approach and what is known about genetic and environmental mechanisms in a variety of common diseases. It seeks to clarify the goals of human genetic research by providing state-of-the art insights into known molecular mechanisms underlying common disease processes while at the same time providing a realistic overview of the expected genetic and physiological complexity.
Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable basis for identifying which patients are most likely to benefit from each treatment. It is oriented to both clinical investigators and statisticians. For clinical investigators, it includes background information on clinical trial design and statistical analysis. For statisticians and others who want to go deeper, it covers state-of-the-art adaptive designs and the development and validation of probabilistic classifiers. The author describes the development and validation of prognostic and predictive biomarkers and their integration into clinical trials that establish their clinical utility for informing treatment decisions for future patients.
With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe’s Intensive Care Medicine offers authoritative guidance to the wide variety of specialty
Until the past decade, clinicians and researchers assumed that the medical evaluation and treatment of both women and men were the same. This archaic and dangerous notion persisted in spite of the clear anatomic and physiologic differences between the genders. Today, we fully understand that this paradigm is false. In all specialties of medicine, practitioners and researchers are beginning to consider the influence of sex and gender and how it should inform the care of their patients. This book focuses on the issue of sex and gender in the evaluation and treatment of patients specifically in the delivery of acute medical care. It serves as a guide both to clinicians interested in the impact of sex and gender on their practice and to researchers interested in the current state of the art in the field and critical future research directions.
Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable basis for identifying which patients are most likely to benefit from each treatment. It is oriented to both clinical investigators and statisticians. For clinical investigators, it includes background information on clinical trial design and statistical analysis. For statisticians and others who want to go deeper, it covers state-of-the-art adaptive designs and the development and validation of probabilistic classifiers. The author describes the development and validation of prognostic and predictive biomarkers and their integration into clinical trials that establish their clinical utility for informing treatment decisions for future patients.
Genes and Common Diseases presents an up-to-date view of the role of genetics in modern medicine, reflecting the strengths and limitations of a genetic perspective. The current shift in emphasis from the study of rare single gene disorders to common diseases brings genetics into every aspect of modern medicine, from infectious diseases to therapeutics. However, it is unclear whether this increasingly genetic focus will prove useful in the face of major environmental influences in many common diseases. The book takes a hard and self-critical look at what can and cannot be achieved using a genetic approach and what is known about genetic and environmental mechanisms in a variety of common diseases. It seeks to clarify the goals of human genetic research by providing state-of-the art insights into known molecular mechanisms underlying common disease processes while at the same time providing a realistic overview of the expected genetic and physiological complexity.
The following publication constitutes a continuation of a longstanding research conducted by both authors on nourishment, dietetics, pharmacology and gastronomy in the Late Antiquity and early Byzanti
* 39 Additional Chapters-over 300 pages of content.* A Complete lmage Bank with more than 1500 images and illustrations, including 500 NEW illustrations, radiographs,and EKGs.* 90 State-of-the-Art Vid
In the popular "Little Bit of" series: a fresh, accessible introduction to the practice of reiki. The Japanese art of reiki can reduce stress, aid relaxation, enhance energy, and promote heali
Throughout history women have practiced the art of medicine and healing. Yet they have always faced difficulties in the medical profession--not only have they struggled to gain acceptance from their m
The best kind of knowledge is uncommon knowledge.Okay, so maybe you know all the stuff you're supposed to know--that there are teenier things than atoms, that Remembrance of Things Past has something
This book explores the cultural history of embryology in Tibet, in culture, religion, art and literature, and what this reveals about its medicine and religion. Filling a significant gap in the litera
