Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex physiological processes of DNA replication and repair. Besi
This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other speciali
This book focuses on the application of fluorescence to study motor proteins (myosins, kinesins, DNA helicases and RNA polymerases). It is intended for a large community of biochemists, biophysicists
Known for flexibility and robustness, PCR techniques continue to improve through numerous developments, including the identification of thermostable DNA polymerases which exhibit a range of propertie
This 1988 volume provides a stimulating survey of the ways in which the DNA-containing organelles of yeast, animal, and plant cells replicate. The orderly division and segregation of these organelles is essential for the survival of all eukaryotes and is therefore a topic of importance to a wide range of biologists: from geneticists, via physiologists, to molecular biologists. The first part of the volume examines the mechanism, regulation and consequences of organelle segregation and division as studied in plant and animal cells. The second part of the volume compares the replication of DNA in eukaryote organelles with bacterial processes. Reviews range from a comparative study of DNA polymerases to the possible mechanisms ensuring DNA segregation. The volume will be of value to anyone with an interest in the areas of biology, genetics, zoology, botany and biochemistry.
Poly (ADP-ribose) Polymerases (PARPs) are abundant and ubiquitous proteins that regulate crucial processes of the cell cycle, DNA repair, genomic stability, and transcriptional regulation.? Being invo