醫藥化學/精要速覽系列先鋒版(簡體書)

“精要速覽系列(Instant Notes Series)”叢書是國外教材“Best Seller”榜的上榜教材。該系列結構新穎，視角獨特；重點明確，脈絡分明；圖表簡明清晰；英文自然易懂，被國內多所重點院校選用作為雙語教材。先鋒版是繼“現代生物學精要速覽”之后推出的跨學科的升級版本。

本書是該系列中的《醫藥化學》分冊，全書共13章，綜合了化學、生物學和計算機科學的內容，扼要介紹了藥物設計與發現、新藥開發與應用、臨床試驗及專利申請等。本書是指導大學生快速掌握醫藥化學基礎知識的優秀教材，也是輔助教師授課的極佳教學參考書，同時可供相關專業的研究生參考。

Abbreviations
Preface
About the author
Section A-The science of medicinal chemistry
　A1 Introduction
　A2 From concept to market
Section B-Drug targets
　B1 Enzymes
　B2 Receptors
　B3 Carrier proteins
　B4 Structural proteins
　B5 Nucleic acids
　B6 Lipids
　B7 Carbohydrates
Section C-Pharmacokinetics
　C1 Pharmacokinetics
　C2 Drug absorption
　C3 Drug distribution
　C4 Drug metabolism
　C5 Drug excretion
　C6 Drug administration
　C7 Drug dosing
Section D-Biological testing and bioassays
　D1 Testing drugs
　D2 Testing drugs in uitro
　D3 Testing drugs in uiuo
Section E-Drug discovery
　E1 The lead compound
　E2 Natural sources of lead compounds
　E3 Synthetic sources of lead compounds
Section F-Synthesis
　F1 Synthetic considerations
　F2 Stereochemistry
　F3 Combinatorial synthesis
Section G-Structure-activity relationships
　G1 Definition of structure-activity relationshiips
　G2 Binding interactions
　G3 Functional groups as binding groups
　G4 The pharmacophore
　G5 Quantitative structure-activity relationships
Section H-Target orientated drug design
　H1 Aims of drug design
　H2 Computer aided drug design
　H3 Simplification of complex molecules
　H4 Conformational restraint
　H5 Extra binding interactions
　H6 Enhancing existing binding interactions
Section I-Pharmacokinetic orientated drug design
　I1 Drug solubility
　I2 Drug stability
Section J-Patenting and manufacture
　J1 Patenting and chemical development
　J2 Optimization of reactions
　J3 Scale-up issues
　J4 Process development
　J5 Specifications
Section K-Preclinical testing and clinical trials
　K1 Toxicology
　K2 Pharmacology and pharamceutical chemistry
　K3 Drug metabolism studies
　K4 Clinical trials
　K5 Regulatory affairs
Section L-Case study:inhibitors of EGF-receptor kinase
　L1 Epidermal growth factor receptor
　L2 Testing procedures
　L3 From lead compound to dianilino-phthalimides
　L4 Modeling studies
　L5 4-(Phenylamino)pyrrolopyrimidines
　L6 Pyrazolopyrimidines
Section M-History of medicinal chemistry
　M1 The age of herbs,potions and magic
　M2 The nineteenth century
　M3 A fledgling science(1900-1930)
　M4 The dawn of the antibacterial age(1930-1945)
　M5 The antibiotic age(1945-1970s)
　M6 The age of reason (1970s to present)
Further reading
Index