Translational Control in Biology And Medicine

This work on translational control--the central idea of which is that gene expression is regulated by the efficiency of utilization of messenger RNA in specifying protein synthesis--is a successor of the earlier Translational Control (1996) and Translational Control of Gene Expression. For their new survey of the current state of the translational control field, Mathews (U. of Medicine and Dentistry of New Jersey, US), Sonenberg (McGill U., Canada), and Hershey (U. of California at Davis, US) stress three themes in presenting the 30 contributions: the engagement of translational control in systems and processes at the cutting edge of biomedical research; fundamental mechanisms and processes related to protein synthesis; and underrepresented but fast-growing areas such as cellular internal ribosomal entry sites, microRNAs, messenger RNA localization, translational control in plants, and riboswitches. Annotation c2007 Book News, Inc., Portland, OR (booknews.com)