Molecular Biology of the Cell: Reference Edition

Ideal for libraries, laboratories, and researchers, this Reference Edition of Molecular Biology of the Cell, Fifth Edition offers an alternative to the student version by providing the complete text of Chapters 1-25 in printed format.*

For nearly a quarter century Molecular Biology of the Cell has been the leading in-depth text reference in cell biology. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter).

The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. Most importantly for scientists and researchers, the free Media DVD, which is packaged with every copy of the book, now contains PowerPoint® presentations with all of the figures, tables and micrographs from the book (available as JPEGs too). Also included is the Media Player with over 125 movies—animations, videos, and molecular models—all with voiceover narration. These PowerPoint slides and movies are ideal for presentations and research talks. And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments.

Molecular Biology of the Cell: Reference Edition is conceptual, accurate and authoritative. An extensive, detailed index provides instant access to the most crucial information and concepts, while a glossary with more than 1,300 entries has been designed for rapid access to technical vocabulary. By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors provide the coherent framework needed to effectively access the primary literature.
* There is also a student textbook version of Molecular Biology of the Cell, Fifth Edition (ISBN 0-8153-4105-9) that contains Chapters 1-20 in printed format, and Chapters 21-25 only in pdf format on the accompanying DVD-ROM.

Bruce Alberts received his PhD from Harvard University and is Professor of Biochemistry and Biophysics at the University of California, San Francisco. For 12 years, he served as President of the U.S. National Academy of Sciences (1993-2005).
Alexander Johnson received his PhD from Harvard University and is Professor of Microbiology and Immunology and Director of the Biochemistry, Cell Biology, Genetics, and Developmental Biology Graduate Program at the University of California, San Francisco.
Julian Lewis received his DPhil from the University of Oxford and is a Principal Scientist at the London Research Institute of Cancer Research UK.
Martin Raff received his MD from McGill University and is at the Medical Research Council Laboratory for Molecular Cell Biology and the Biology Department at University College London.
Keith Roberts received his PhD from the University of Cambridge and is Emeritus Fellow at the John Innes Centre, Norwich.
Peter Walter received his PhD from The Rockefeller University in New York and is Professor and Chairman of the Department of Biochemistry and Biophysics at the University of California, San Francisco, and an Investigator of the Howard Hughes Medical Institute.

PART I INTRODUCTION TO THE CELL 1. Cells and Genomes 2. Cell Chemistry and Biosynthesis 3. Proteins PART II BASIC GENETIC MECHANISMS 4. DNA, Chromosomes, and Genomes 5. DNA Replication, Repair, and Recombination 6. How Cells Read the Genome: From DNA to Protein 7. Control of Gene Expression PART III METHODS 8. Manipulating Proteins, DNA, and RNA 9. Visualizing Cells PART IV INTERNAL ORGANIZATION OF THE CELL 10. Membrane Structure 11. Membrane Transport of Small Molecules and the Electrical Properties of Membranes 12. Intracellular Compartments and Protein Sorting 13. Intracellular Vesicular Traffic 14. Energy Conversion: Mitochondria and Chloroplasts 15. Mechanisms of Cell Communication 16. The Cytoskeleton 17. The Cell Cycle 18. Apoptosis PART V CELLS IN THEIR SOCIAL CONTEXT 19. Cell Junctions, Cell Adhesion, and the Extracellular Matrix 20. Cancer 21. Sexual Reproduction: Meiosis, Germ Cells, and Fertilization 22. Development of Multicellular Organisms 23. Specialized Tissues, Stem Cells, and Tissue Renewal 24. Pathogens, Infection, and Innate Immunity 25. The Adaptive Immune System

* There is also a student textbook version of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4105-5) that contains Chapters 1-20 in printed format, and Chapters 21-25 only in pdf format on the accompanying DVD-ROM.