Biocatalysis For Green Chemistry And Chemical Process Development

The book is aimed to facilitate the industrial applications of this powerful and emerging green technology, and catalyze the advancement of the technology itself.

ROMAS JOSEPH KAZLAUSKAS is Professor of Biochemistry, Molecular Biology and Biophysics at the BioTechnology Institute of the University of Minnesota, Twin Cities. He is the coauthor of over eighty papers and reviews, and the book Hydrolases in Organic Synthesis. He also served as the co-chair of two Gordon Research Conferences, one on biocatalysis and one on green chemistry.

1. Overview of Biotechnology Tools for Green Synthesis: Enzymes, Cells and their Tunability by Engineering.

2. How Green can the Industry Become with Biotechnology.

3. Emerging Enzymes and Their Synthetic Applications.

4. Reaction Efficiencies and Green Chemistry Metrics of Biotransformations.

II. Application and Case Studies – Pharmaceuticals and Fine Chemicals.

5. Biocatalytic Routes to Chiral Intermediates for Development of Drugs.

6. Transflutaminase for Protein Drug Modification: PEGylation and Beyond.

7. Microbial Production of Plant-Derived Pharmaceutical Natural Products through Metabolic Engineering: Artemisinin and Beyond.

8. Toward Greener Therapeutic Proteins.

III. Application and Case Studies – Flavor & Fragrance, Agrochemicals and Fine Chemicals.

9. Opportunities for Biocatalysis in the Flavor, Fragrance and Cosmetic Industry.

10. Application of Biocatalysis in the Agrochemical Industry.

11. Green Production of Fine Chemicals by Isolated Enzymes.

12. Whole Cell Production of Fine Chemicals and Intermediates.

IV. Applications and Case Studies – Polymers and Renewable Chemicals.

13. Green Chemistry for the Production of Biodegradable, Biorenewable, Biocompatible Polymers.

14. Enzymatic Degradation of Lignocellulosic Biomass.

15. Bioconversion of Renewable-Plant Oils.

16. Microbial Bioprocesses for Industrial Scale Chemical Production.