CLINICAL DILEMMAS IN DIABETES

Robert Rizza Professor of Medicine and Division Chair for Endocrinology, Mayo Clinic College of Medicine, Rochester, USA

Preface.

Part I Prediabetes and the Diagnosis of Diabetes.

1 Is prediabetes a risk factor or is it a disease? (Kalpana Muthusamy and Adrian Vella).

2 Early diagnosis of type 1 diabetes: Useful or a phyrrhic victory? (Chiara Guglielmi and Paolo Pozzilli).

3 How should secondary causes of diabetes be excluded? (Aonghus O'Loughlin and Sean F. Dinneen).

4 Screening patients with prediabetes and diabetes for cardiovascular disease (Deepika S. Reddy and Vivian Fonseca).

Part II Initial Evaluation and Management of Diabetes.

5 What is the role of self-monitoring in diabetes? Is there a role for postprandial glucose monitoring? How does continuous glucose monitoring integrate into clinical practice? (Rami Almokayyad and Robert Cuddihy).

6 The optimal diet for diabetes is? (Maria L. Collazo-Clavell).

7 How to determine when to pursue lifestyle change alone versus pharmacotherapy at diagnosis? (Galina Smushkin and F. John Service).

8 Insulin sensitizers versus secretagogues as first-line therapy for diabetes: Rationale for clinical choice (Robert J. Richards, L. Yvonne Melendez-Ramirez, and William T. Cefalu).

9 Are insulin sensitizers useful additions to insulin therapy? (John W. Richard III and Philip Raskin).

10 Is there a role for incretin-based therapy in combination with insulin? (Matheni Sathananthan and Adrian Vella).

11 HbA1c: Is it the most important therapeutic target in outpatient management of diabetes? (Steven A. Smith).

Part III Management of Associated Risk Factors and Disease.

12 Primary therapy for obesity as the treatment of type 2 diabetes (Manpreet S. Mundi and Michael D. Jensen).

13 Are statins the optimal therapy for cardiovascular risk in patients with diabetes? Are triglycerides an important independent risk factor for diabetes? (Michael O'Reilly and Timothy O'Brien).

14 The role of bariatric surgery in obese patients with diabetes: Primary or rescue therapy? (Praveena Gandikota and Blandine Laferrere).

15 Hyperglycemia should be avoided in critical illness and the postoperative period (Kalpana Muthusamy and John M. Miles).

16 Is there an optimal revascularization strategy in diabetic patients with ischemic heart disease? (Stephen H. McKellar, Morgan L. Brown, and Robert L. Frye).

Index.