Nickel And Its Surprising Impact In Nature - Metal Ions In Life Sciences V 2

Volume 2 focuses on the vibrant research area concerning nickel as well as its complexes and their role in Nature. With more than 2,800 references and over 130 illustrations, it is an essential resource for scientists working in the wide range from inorganic biochemistry all the way through to medicine.

In 17 stimulating chapters, written by 47 internationally recognized experts, Nickel and Its Surprising Impact in Nature highlights critically the biogeochemistry of nickel, its role in the environment, in plants and cyanobacteria, as well as for the gastric pathogen Helicobacter pylori, for gene expression and carcinogenensis. In addition, it covers the complex-forming properties of nickel with amino acids, peptides, phosphates, nucleotides, and nucleic acids. The volume also provides sophisticated insights in the recent progress made in understanding the role of nickel in enzymes such as ureases, hydrogenases, superoxide dismutases, acireductone dioxygenases, acetyl-coenzyme A synthases, carbon monoxide dehydrogenases, methyl-coenzyme M reductases...and it reveals the chaperones of nickel metabolism.

Helmut Sigel is Emeritus Professor (2003) of Inorganic Chemistry at the University of Basel, Switzerland, and a previous editor of the MIBS series until Volume 44. He serves on various editorial and advisory boards, published over 300 articles on metal ion complexes of nucleotides, coenzymes, and other ligands of biological relevance, and lectured worldwide. He was named Protagonist in Chemistry (2002) by ICA (issue 339); among further honors are the P. Ray Award (Indian Chemical Society, of which he is also an Honorary Fellow), the Werner Award (Swiss Chemical Society), a Doctor of Science honoris causa degree (Kalyani University, India), appointments as Visiting Professor (e.g., Austria, China, UK) and Endowed Lectureships.

Roland K.O. Sigel is Assistant Professor (2003) of Inorganic Chemistry at the University of Zürich, Switzerland, endowed with a Förderungsprofessur of the Swiss National Science Foundation. He received his doctoral degree summa cum laude (1999) from the University of Dortmund, Germany, working with Bernhard Lippert; thereafter he spent nearly three years at Columbia University, New York, USA, in the group of Anna Marie Pyle (now Yale University); during the six years abroad he received several fellowships from various sources. His research focuses on the structural and catalytic role of metal ions in ribozymes, especially group II introns, and on related topics. He was also an editor of Volumes 43 and 44 of the MIBS series.

2 NICKEL IN THE ENVIRONMENT AND ITS ROLE IN THE METABOLISM OF PLANTS AND CYANOBACTERIA (Hendrik Küpper and Peter M. H. Kroneck).

3 NICKEL ION COMPLEXES OF AMINO ACIDS AND PEPTIDES (Teresa Kowalik-Jankowska, Henryk Kozlowski, Etelka Farkas, and Imre Sóvágó).

4 COMPLEX FORMATION OF NICKEL(II) AND RELATED METAL IONS WITH SUGAR RESIDUES, NUCLEOBASES, PHOSPHATES, NUCLEOTIDES, AND NUCLEIC ACIDS (Roland K. O. Sigel and Helmut Sigel).

5 SYNTHETIC MODELS FOR THE ACTIVE SITES OF NICKEL-CONTAINING ENZYMES (Jarl Ivar van der Vlugt and Franc Meyer).

6 UREASE: RECENT INSIGHTS ON THE ROLE OF NICKEL (Stefano Ciurli).

7 NICKEL IRON HYDROGENASES (Wolfgang Lubitz, Maurice van Gastel, and Wolfgang Gärtner).

8 METHYL-COENZYME M REDUCTASE AND ITS NICKEL CORPHIN COENZYME F₄₃₀ IN METHANOGENIC ARCHAEA (Bernhard Jaun and Rudolf K. Thauer).

9 ACETYL-COENZYME A SYNTHASES AND NICKEL-CONTAINING CARBON MONOXIDE DEHYDROGENASES (Paul A. Lindahl and David E. Graham).

10 NICKEL SUPEROXIDE DISMUTASE (Peter A. Bryngelson and Michael J. Maroney).

11 BIOCHEMISTRY OF THE NICKEL-DEPENDENT GLYOXALASE I ENZYMES (Nicole Sukdeo, Elisabeth Daub, and John F. Honek).

12 NICKEL IN ACIREDUCTONE DIOXYGENASE (Thomas C. Pochapsky, Tingting Ju, Marina Dang, Rachel Beaulieu, Gina M. Pagani, and Bo OuYang).

13 THE NICKEL-REGULATED PEPTIDYL PROLYL CIS/TRANS ISOMERASE SlyD (Frank Erdmann and Gunter Fischer).

14 CHAPERONES OF NICKEL METABOLISM (Soledad Quiroz, Jong K. Kim, Scott B. Mulrooney, and Robert P. Hausinger).

15 THE ROLE OF NICKEL IN ENVIRONMENTAL ADAPTATION OF THE GASTRIC PATHOGEN HELICOBACTER PYLORI (Florian D. Ernst, Arnoud H. M. van Vliet, Manfred Kist, Johannes G. Kusters, and Stefan Bereswill).

16 NICKEL-DEPENDENT GENE EXPRESSION (Konstantin Salnikow and Kazimierz S. Kasprzak).

17 NICKEL TOXICITY AND CARCINOGENESIS (Kazimierz S. Kasprzak and Konstantin Salnikow).

SUBJECT INDEX.