Injectable Drug Development ─ Techniques to Reduce Pain and Irritation

Filled with strategies for minimizing the adverse effects of injectable drugs, this book provides the scientific background and techniques required to evaluate parenteral formulations with respect to their potential to cause pain, irritation, and muscle damage. The book's editors have selected contributors from the areas of pharmaceutics, physiology, anatomy, toxicology, and product formulation. Using a unique, interdisciplinary approach, they cover topics such as muscle damage with injectables, in vitro and in vivo cystolic enzyme release, histological and morphological methods, assessing pain, cosolvents in injectables, biodegradable microparticles, and more.