Studies on Periodontal Disease

The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease.

This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.

Dr. Daisuke Ekuni, DDS, PhD, is currently Lecturer, Okayama University Hospital, Department of Preventive Dentistry, Okayama, Japan where he also completed his DDS and PhD in Dental Science. He was a Post-Doctoral Fellow in the Department of Oral Biological & Medical Sciences at the University of British Columbia, Vancouver, Canada. Dr. Ekuni is a member of several professional societies including the International Associate for Dental Research and the Japanese Society of Periodontology.

Dr. Maurizio Battino, DSc, PhD, earned his DSc at the University of Bologna and his PhD in Biochemistry at the University of Catania, Italy. He was a Post-Doctoral Fellow at the University of Granada and is currently Associate Professor in Biochemistry at Universita Politecnica delle Marche. He serves on the editorial boards of several journals including as Editor-in-Chief for Journal of Berry Research. His laboratory focuses on: the healthy effects of bioactive compounds in berries, honey and olive oil; unraveling the role of oxidative stress in the onset and development of periodontal diseases; and the mitochondrial role in genetic diseases.

Dr. Takaaki Tomofuji, DDS, PhD, is Senior Assistant Professor, Okayama University Hospital, Department of Preventive Dentistry, Okayama, Japan. He was a Post-Doctorial Fellow at the Chonbuk National University, South Korea. He is a councilor of the Japanese Society for Dental Health and serves on the editorial board of Journal of Dental Health.

Dr. Edward E Putnins, DMD; Dip Perio; MRCD(C); MSc; PhD received his undergraduate and Periodontal training at The University of Manitoba prior to completion of his PhD at The University of British Columbia. He is a professor and serves as Associate Dean of Research, Graduate and Postgraduate Studies at The University of British Columbia. Dr. Putnins’ laboratory has two principal areas of focus: (1) examining whether novel bone marrow stromal cell expansion strategies can be developed to regenerate lost hard and soft periodontal tissues; and (2) regulating epithelial cell barrier integrity and proliferation with respect to periodontal disease pathogenesis.