Introductory Adaptive Trial Designs ─ A Practical Guide With R

Instead of providing black box-like general commercial software packages, this tutorial-style book develops the R functions and algorithms necessary to customize adaptive designs to meet their needs. Designed as a practical, tutorial style resource, the book provides a 30 minute R tutorial and includes simulations for all examples.

Mark Chang is vice president of biometrics at AMAG Pharmaceuticals and an adjunct professor at Boston University. Dr. Chang is an elected fellow of the American Statistical Association and a co-founder of the International Society for Biopharmaceutical Statistics. He serves on the editorial boards of statistical journals and has published eight books, includingPrinciples of Scientific Methods, Paradoxes in Scientific Inference,Modern Issues and Methods in Biostatistics, Monte Carlo Simulation for the Pharmaceutical Industry, andAdaptive Design Theory and Implementation Using SAS and R, Second Edition.