Chirality In Supramolecular Assemblies - Causes And Consequences

Chirality in Supramolecular Assemblies: Causes and Consequences presents a broad overview of this important and rapidly developing interdisciplinary field. The book begins with an introduction to fundamental principles, followed by comprehensive coverage of recent developments in synthesis and applications of supramolecular chirality across inorganic, organometallic, organic and biological chemistry.

The book is divided into three sections as follows:

Fundamentals: A general treatment of the principles, including an introduction to molecular and topological chirality, the origins of homochirality, the nature and potential complexity of supramolecular assemblies, and the concept of molecular recognition.
Inorganic/Organometallic Systems: Covers the solution phase (including molecular devices and machines), the solid state (including network solids and coordination polymers), and surfaces/interfaces (including chiral separations and chiral catalysis).
Organic/biological systems: Covers six classes of compounds; cucurbiturils; cyclodextrins; calixarenes; synthetic peptides, crown ethers and cyclophanes; micelles and nanoparticles; proteins and other biological macromolecules. For each class of compound there is a discussion of molecular recognition/selective binding and catalysis.

Emeritus Professor F. Richard Keene
Adjunct Professor of Chemistry, School of Pharmacy & Molecular Sciences, James Cook University, Australia and Department of Chemistry, University of Canterbury, New Zealand. Honorary Visiting Research Fellow, School of Chemistry & Physics, University of Adelaide
Richard Keene is an acknowledged international authority on stereochemistry in coordination chemistry - and significantly, in the control of stereochemistry within polymetallic supramolecular assemblies - and has over the last decade has published widely on (i) its effect on intramolecular electron and energy transfer in such assemblies, and (ii) its influence on sequence- and structure-selectivity in the interaction of such complexes with nucleic acids, and their cytotoxicity to cancer cells and bacteria. He has over 160 publications (h-index 44), as well 6 chapters in monographs and a patent.