Bone Marrow Regeneration in Mouse by using Bone Marrow derived Stem Cells

A book on Bone Marrow Regeneration in Mouse by using Bone Marrow derived Stem Cells. Bone marrow, a dynamic organ of a mammalian body, carries fundamentally of water, protein, and fat. These ingredients vary from person to person and within the same individual over time. Bone marrow is a delicate, jellied, and powerful tissue which serves as an organ of the immune system. It is restrained in the center and the epiphysis of long bones like femora, tibia, humeri, ribs, pelvis, vertebrae, and skull of the body [2]. Bone marrow holds cellular component and soluble component. The cellular component comprises stem cells such as hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), multipotent adult progenitor cells (MAPCs) and stroma cells of bone marrow such as endothelial cells (ECs), osteoclasts, osteoblasts, fibroblasts, tissue macrophages, and adipocytes, and the soluble component constitutes of cytokines, chemokines, growth factors, and hormones [3]. Bone marrow comprises two cellular components, parenchyma or hematopoietic component which includes HSCs and hematopoietic progenitor cells (HPCs) and stoma or vascular component bears non-hematopoietic progenitor cells such as endothelial cells.