Effects of Murraya Koenigii Leaves in Streptozotocinnicotinamide and High Fructose

Diabetes is a chronic, progressive, metabolic disease characterized by elevated levels of blood glucose. The basic pathology is either pancreas does not produce enough insulin or cells cannot respond to insulin Diabetes leads over time to serious damage to the heart, blood vessels, eyes, kidneys, and nerves 2. Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia and alterations in metabolism of carbohydrate, lipid, and protein, associated with alteration of insulin secretion and/or action'. DM is a metabolic disorder, alarmingly increase in the incidence observed globally. There is a globally agreed target to halt the rise in diabetes and obesity by 2025 I. It is considered as a major threat to human health in the developing and developed countries due to its canplications. In spite of control of DM, complications may develop over due course of disease. Lifestyle and food habit changes are known to be the major contributing factors of diabetes