Electrochemical Sensors for Biomedical Applications: Chapter - 1: Metal Nanocomposites-Based Sensor Transducer

This book chapter describes metal nanocomposites-derived electrochemical sensor and biosensor platforms for the sensitive and selective detection of emergent biomarkers. The electrochemical sensor offers numerous advantageous features, including cost-effective and ease of miniaturization, rapid and online monitoring, simultaneous detection ability, etc., which have captivated the potential interdisciplinary research. In specific, this chapter highlights the advances and challenges towards the electrochemical detection of emergent biomarkers such as hydrogen peroxide, nitric oxide, β-nicotinamide adenine acetaminophen, dinucleotide (NADH) in biofluids. In fact, the effective utility and benefits of transition metal nanocomposites without the utilization of biological materials, including enzymes, antibodies, etc. as electrode materials towards the detection of selected biomarkers in practical biofluids, monitoring early-stage and diagnosis of disease-related biomarkers, are also described. These promising metal nanomaterials-based electrochemical sensor platforms concrete the tactic for a new generation of sensing devices.
Moreover, I am pretty sure that this chapter will improve the confidence of young researchers and students to think and tackle research problems in the field of bio-analytical chemistry. I highly believe that this chapter will go a long way to satisfy the long-felt need of young researchers/students for a friendly guide on electrochemical sensors.
Thank you,
Dr. Govindhan Maduraiveeran