One of the first studies of an exciting new development in global biotechnology, this cutting edge text examines the extent of the transnational movements of tissues, stem cells, and expertise, in the
The group of chemicals known collectively as neurotransmitters form the basis of a complex communication system between nerve cells. It is a system which is constantly subtly refined and regulated via the modulating action of other neurotransmitters, circulating hormones, the products of local tissues and the action of various drugs (from both medicinal and socially abused sources). Within this book, acknowledged authorities concisely describe the basic mechanisms involved in neurotransmitter release modulation in the different parts of the nervous system. This includes a quantitative evaluation of the significance of modulation, and a summary of both its biological ramifications and potential clinical relevance. The clear illustrations and descriptions create a valuable and easy to use reference resource for the non-specialist reader and neuroscientist alike. Clinicians, researchers and students should all find its contents of interest.
In studying the dynamics of populations, whether of animals, plants or cells, it is crucial to allow for intrinsic delays, due to such things as gestation, maturation or transport. This book is concerned with one of the fundamental questions in the analysis of the effect of delays, namely determining whether they effect the stability of steady states. The analysis is presented for one or two such delays treated both as discrete, where an event which occurred at a precise time in the past has an effect now, and distributed, where the delay is averaged over the population's history. Both of these types occur in biological contexts. The method used to tackle these questions is linear stability analysis which leads to an understanding of the local stability. By avoiding global questions, the author has kept the mathematical prerequisites to a minimum, essentially advanced calculus and ordinary differential equations.
In the history of Norman monasteries founded in Ireland, the Benedictine priory of Fore stands apart. While many foundations were independent entities and others were cells or priories of English foun
Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediat
In studying the dynamics of populations, whether of animals, plants or cells, it is crucial to allow for intrinsic delays, due to such things as gestation, maturation or transport. This book is concerned with one of the fundamental questions in the analysis of the effect of delays, namely determining whether they effect the stability of steady states. The analysis is presented for one or two such delays treated both as discrete, where an event which occurred at a precise time in the past has an effect now, and distributed, where the delay is averaged over the population's history. Both of these types occur in biological contexts. The method used to tackle these questions is linear stability analysis which leads to an understanding of the local stability. By avoiding global questions, the author has kept the mathematical prerequisites to a minimum, essentially advanced calculus and ordinary differential equations.
How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical sign
