This important new reference book on human cancer provides a global picture of the epidemiology of cancer and its environmental causes. By summarising on a cancer-by-cancer basis geographical, environmental and ethical factors, the volume collates a wealth of information which, taken together, provides valuable insights into the causes of cancer and scope for its elimination and control. The contents include: (1) general epidemiological methods; (2) a review of known or suspected causes; (3) a detailed review of specific cancers; (4) a brief review of legal and ethical implications. The bibliography concentrates on recent key references and reviews.
Polycyclic aromatic hydrocarbons, many of which have been identified as potent human carcinogens, occur widely in the environment as a result of incomplete combustion of fossil fuels and other organic matter. Major sources of emissions arise from wood and coal burning, automobiles, heat and power plants, and refuse burning. Their widespread occurrence in the air and in food and water underlines the importance of understanding their role as causes of human cancer. This 1991 volume was the first to review the chemical properties of these carcinogens and to relate their carcinogenic activity to their metabolic by-products within the body. The emphasis throughout is on those recent findings, newer methods and techniques which helped to illuminate the process of carcinogenesis. The volume is suitable for anyone with a professional interest in the chemistry and metabolism of polycyclic aromatic hydrocarbons, environmental chemistry and chemical carcinogenesis.
This important new reference book on human cancer provides a global picture of the epidemiology of cancer and its environmental causes. By summarising on a cancer-by-cancer basis geographical, environmental and ethical factors, the volume collates a wealth of information which, taken together, provides valuable insights into the causes of cancer and scope for its elimination and control. The contents include: (1) general epidemiological methods; (2) a review of known or suspected causes; (3) a detailed review of specific cancers; (4) a brief review of legal and ethical implications. The bibliography concentrates on recent key references and reviews.
Originally published in 1992, this volume looks in depth at the carcinogenic properties of N-nitroso compounds. These compounds occur widely in smoked foods and in meat and fish cured with nitrates; they are also formed in some industrial processes and in addition are found in cosmetics, tobacco and tobacco smoke. By focusing on the chemical and biological properties, the volume attempts to explain how these compounds exert their carcinogenic potential and, furthermore, goes on to explain how apparently harmless precursors such as nitrates and amines are transformed to produce carcinogens.
