Correction Techniques in Emission Tomographic Imaging

Written by an interdisciplinary team of medical doctors, computer scientists, physicists, engineers, and mathematicians, Correction Techniques in Emission Tomography presents various correction methods used in emission tomography to generate and enhance images. It discusses the techniques from a computer science, mathematics, and physics viewpoint.

The book gives a comprehensive overview of correction techniques at different levels of the data processing workflow. It covers nuclear medicine imaging, hybrid emission tomography (PET-CT, SPECT-CT, PET-MRI, PET-ultrasound), and optical imaging (fluorescence molecular tomography). It illustrates basic principles as well as recent advances, such as model-based iterative algorithms and 4D methods. An important aspect of the book is on new and sophisticated motion correction techniques in PET imaging. These techniques enable high-resolution, high-quality images, leading to better imaging analysis and image-based diagnostics.

Reflecting state-of-the-art research, this volume explores the range of problems that occur in emission tomography. It looks at how the resulting images are affected and presents practical compensation methods to overcome the problems and improve the images.

Mohammad Dawood is a researcher at the European Institute for Molecular Imaging. He earned a PhD in computer science from the University of Münster. His research interests include motion correction and tumor segmentation in medical imaging as well as biometrics and pattern analysis in image analysis.
Xiaoyi Jiang is a professor at the University of Münster and a scientist at the European Institute for Molecular Imaging. An IEEE senior member and an IAPR fellow, he earned a PhD in computer science from the University of Bern. His research areas include medical imaging analysis, pattern recognition, and computer vision.
Klaus Schäfers is head of the technology group at the European Institute for Molecular Imaging. He earned a PhD in medical physics from the University of Münster. His research interests include quantitative PET, motion detection and correction, high-resolution PET, multimodal molecular imaging techniques, and molecular imaging information in radiation therapy planning.

Introduction, Klaus SchäfersIntroduction Principle of Emission Tomography Electromagnetic Spectrum Need for Correction Techniques
BACKGROUNDBiomedical Applications of Emission Tomography, Michael Schäfers, Sven Hermann, Sonja Schäfers, Thomas Viel, Marilyn Law, and Andreas H. JacobsThe role of imaging in biomedical research and applications Functional and molecular imaging by emission tomography enables high sensitivity and spatial resolution Biomedical applications of emission tomography depend on tracers Applications
PET Image Reconstruction, Frank WübbelingIntroduction Analytical algorithmsDiscrete algorithmsSummary
CORRECTIONS TECHNIQUES IN PET AND SPECT Basics of PET and SPECT Imaging, Ralph A. Bundschuh and Sibylle I. ZieglerIntroduction
Corrections for Physical Factors, Florian BütherIntroduction Decay correction Randoms correctionAttenuation correctionScatter correctionConcluding remarks
Corrections for Scanner Related Factors, Marc HuismannPositron emission tomographySingle photon emission computed tomography
Image Processing Techniques in Emission Tomography, Fabian Gigengack, Michael Fieseler, Daniel Tenbrinck, and Xiaoyi JiangIntroduction Denoising Interpolation RegistrationPartial volume correctionSuper-resolution Validation
Motion Correction in Emission Tomography, Mohammad DawoodIntroductionMotion correction on 3D PET dataOptical flowLucas/Kanade optical flow Horn/Schunck optical flow Bruhn optical flow Preserving discontinuities Correcting for motion Mass conservation-based optical flow
Combined Correction and Reconstruction Methods, Martin Benning, Thomas Kösters, and Frederic LamareIntroduction Parameter identificationCombined reconstruction and motion correctionCombination of parameter identification and motion estimation
RECENT DEVELOPMENTS Introduction into Hybrid Tomographic Imaging, Hartwig NewigerIntroduction Combining PET and SPECT The combination with MR Combining ultrasound with PET and SPECT
MR-Based Attenuation Correction for PET/MR, Matthias Hofmann, Bernd Pichler, and Thomas BeyerIntroduction MR-AC for brain applicationsMethods for torso imaging DiscussionConclusion
Optical Imaging, Angelique Ale and Vasilis NtziachristosIntroduction Fluorescence molecular tomography (FMT)FMT and hybrid FMT systems
Index

References appear at the end of each chapter.